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      MicroRNAs: target recognition and regulatory functions.

      Cell

      metabolism, genetics, MicroRNAs, Humans, Gene Expression Regulation, Animals, 3' Untranslated Regions

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          Abstract

          MicroRNAs (miRNAs) are endogenous approximately 23 nt RNAs that play important gene-regulatory roles in animals and plants by pairing to the mRNAs of protein-coding genes to direct their posttranscriptional repression. This review outlines the current understanding of miRNA target recognition in animals and discusses the widespread impact of miRNAs on both the expression and evolution of protein-coding genes.

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          Journal
          19167326
          3794896
          10.1016/j.cell.2009.01.002

          Chemistry

          metabolism, genetics, MicroRNAs, Humans, Gene Expression Regulation, Animals, 3' Untranslated Regions

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