Highly Enantio- and Diastereoselective Reactions of γ-Substituted Butenolides Through Direct Vinylogous Conjugate Additions

Zhang, Wen Wen; Tan, Davin; Lee, Richmond; Tong, Guanghu; Chen, Wenchao; Qi, Baojian; Huang, Kuo-Wei; Tan, Choon-Hong; Jiang, Zhiyong

doi:10.1002/ange.201205872

Record: found
Abstract: not found
Article: not found

Highly Enantio- and Diastereoselective Reactions of γ-Substituted Butenolides Through Direct Vinylogous Conjugate Additions

Author(s): Wen Zhang , Davin Tan , Richmond Lee , Guanghu Tong , Wenchao Chen , Baojian Qi , Kuo-Wei Huang , Choon-Hong Tan , Zhiyong Jiang

Publication date (Electronic): September 05 2012

Journal: Angewandte Chemie

Publisher: Wiley

Read this article at

ScienceOpenPublisher

Bookmark

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Related collections

Most cited references 75

Record: found
Abstract: found
Article: not found

Fluorine in medicinal chemistry.

Sophie Purser, Peter R. Moore, Steve Swallow … (2008)

It has become evident that fluorinated compounds have a remarkable record in medicinal chemistry and will play a continuing role in providing lead compounds for therapeutic applications. This tutorial review provides a sampling of renowned fluorinated drugs and their mode of action with a discussion clarifying the role and impact of fluorine substitution on drug potency.