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      A nationwide survey on producer and veterinarian perceptions of the painfulness of procedures and disease states in dairy and beef cattle

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          Abstract

          Failure to adequately manage pain in cattle causes suffering and is thus a welfare concern for the livestock industry. The objectives of this study were to summarize caregiver perceptions of the painfulness of various procedures and disease conditions in cattle. This survey also assessed factors that impact the perception of painfulness and determined relationships between pain perception and mitigation in producers and veterinarians in the United States beef and dairy cattle industries. An online survey was distributed via organization listservs and social media groups representing beef and dairy veterinarians and producers. The survey included questions about respondent demographics and pain perception and frequency of pain mitigation use for a variety of common husbandry procedures and disease conditions in cattle less than 2 months, 2–12 months, and greater than 12 months of age. Descriptive statistics were generated, and ordinal logistic regressions were used to assess the relationship between perceived pain level, frequency of pain mitigation use, and respondent demographic factors (e.g., gender, age, and role). There was a relatively low percentage of respondents that identified there was “no pain” associated with the listed procedures and conditions. Across the majority of procedures and conditions and cattle age categories, men perceived procedures to be less painful than women ( P < 0.05). Veterinarians and producer-veterinarians perceived procedures to be more painful than producers ( P < 0.05) for the majority of procedures and conditions. There were some differences identified between respondent age groups in pain perception but the trends were not consistent across procedures and conditions. There was a significant positive linear trend, with greater perceived pain associated with greater likelihood of providing local and systemic analgesia for all procedures and conditions across all cattle age categories ( P ≤ 0.02). Perception of pain is complex and multifactorial, and it influences the likelihood to treat pain in cattle. This research highlighted the importance of understanding how these factors may play a role in increasing the use of pain mitigation within the beef and dairy industries.

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          Sex differences in pain and pain inhibition: multiple explanations of a controversial phenomenon.

          A clear majority of patients with chronic pain are women; however, it has been surprisingly difficult to determine whether this sex bias corresponds to actual sex differences in pain sensitivity. A survey of the currently available epidemiological and laboratory data indicates that the evidence for clinical and experimental sex differences in pain is overwhelming. Various explanations for this phenomenon have been given, ranging from experiential and sociocultural differences in pain experience between men and women to hormonally and genetically driven sex differences in brain neurochemistry.
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            Qualitative sex differences in pain processing: emerging evidence of a biased literature

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              A systematic literature review of 10 years of research on sex/gender and experimental pain perception - part 1: are there really differences between women and men?

              The purpose of this systematic review was to summarize and critically appraise the results of 10 years of human laboratory research on pain and sex/gender. An electronic search strategy was designed by a medical librarian and conducted in multiple databases. A total of 172 articles published between 1998 and 2008 were retrieved, analyzed, and synthesized. The first set of results (122 articles), which is presented in this paper, examined sex difference in the perception of laboratory-induced thermal, pressure, ischemic, muscle, electrical, chemical, and visceral pain in healthy subjects. This review suggests that females (F) and males (M) have comparable thresholds for cold and ischemic pain, while pressure pain thresholds are lower in F than M. There is strong evidence that F tolerate less thermal (heat, cold) and pressure pain than M but it is not the case for tolerance to ischemic pain, which is comparable in both sexes. The majority of the studies that measured pain intensity and unpleasantness showed no sex difference in many pain modalities. In summary, 10 years of laboratory research have not been successful in producing a clear and consistent pattern of sex differences in human pain sensitivity, even with the use of deep, tonic, long-lasting stimuli, which are known to better mimic clinical pain. Whether laboratory studies in healthy subjects are the best paradigm to investigate sex differences in pain perception is open to question and should be discussed with a view to enhancing the clinical relevance of these experiments and developing new research avenues. Copyright © 2011 International Association for the Study of Pain. Published by Elsevier B.V. All rights reserved.
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                Author and article information

                Contributors
                Journal
                Front Pain Res (Lausanne)
                Front Pain Res (Lausanne)
                Front. Pain Res.
                Frontiers in Pain Research
                Frontiers Media S.A.
                2673-561X
                2673-561X
                01 February 2023
                2023
                : 4
                : 1059224
                Affiliations
                [ 1 ]Department of Animal Sciences, Colorado State University , Fort Collins, CO, United States
                [ 2 ]Department of Statistics, Colorado State University , Fort Collins, CO, United States
                [ 3 ]Department of Psychology, Colorado State University , Fort Collins, CO, United States
                [ 4 ]Department of Anatomy and Physiology, Kansas State University , Manhattan, KS, United States
                Author notes

                Edited by: Adroaldo José Zanella, University of São Paulo, Brazil

                Reviewed by: Kenny Rutherford, Scotland's Rural College, United Kingdom Andrew Bell, University of Glasgow, United Kingdom

                [* ] Correspondence: Lily N. Edwards-Callaway lily.edwards-callaway@ 123456colostate.edu

                Specialty Section: This article was submitted to Veterinary and Comparative Pain, a section of the journal Frontiers in Pain Research

                Article
                10.3389/fpain.2023.1059224
                9929155
                a7d0397a-865a-43bf-ad53-71a8c4c9e251
                © 2023 Edwards-Callaway, Keller, Oselinsky, Johnstone, Cramer, Román-Muñiz, Stallones and Coetzee.

                This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

                History
                : 01 October 2022
                : 06 January 2023
                Page count
                Figures: 0, Tables: 4, Equations: 0, References: 108, Pages: 0, Words: 0
                Categories
                Pain Research
                Original Research

                analgesia,castration,cow,lameness,mitigation,pain,welfare
                analgesia, castration, cow, lameness, mitigation, pain, welfare

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