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Abstract
Endothelins are important mediators of physiological and pathophysiologic processes
including cardiovascular disorders, pulmonary disease, renal diseases and many others.
Additionally, endothelins are involved in many other important processes such as development,
cancer biology, wound healing, and even neurotransmission. Here, we review the cell
and molecular biology as well as the prominent pathophysiological aspects of the endothelin
system.
Copyright (c) 2010. Published by Elsevier Inc.