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Germline stem cell transplantation and transgenesis.

Publication date: 2002-06-21

Keywords: Animals, Cell Differentiation, Cell Separation, Cells, Cultured, Cryopreservation, Humans, Male, Seminiferous Tubules, cytology, Sertoli Cells, physiology, Spermatogenesis, Spermatogonia, Stem Cell Transplantation, Stem Cells, Testis, Transduction, Genetic, Transgenes, Transplantation, Heterologous

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Abstract

The recently developed testis cell transplantation method provides a powerful approach to studying the biology of the male germline stem cell and its microenvironment, the stem cell niche. The technique also is being used to examine spermatogenic defects, correct male infertility, and generate transgenic animals.

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PubMed ID:: 12077400

DOI:: 10.1126/science.1071607

ScienceOpen disciplines: Chemistry

Keywords: Animals,Cell Differentiation,Cell Separation,Cells, Cultured,Cryopreservation,Humans,Male,Seminiferous Tubules,cytology,Sertoli Cells,physiology,Spermatogenesis,Spermatogonia,Stem Cell Transplantation,Stem Cells,Testis,Transduction, Genetic,Transgenes,Transplantation, Heterologous

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ScienceOpen disciplines: Chemistry

Germline stem cell transplantation and transgenesis.

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Stress signalling in stem cells

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