LCZ696 (sacubitril/valsartan) protects against cyclophosphamide-induced nephrotoxicity in adult male rats: Up-regulation of Apelin-13/ACE2, miR-200, and down-regulation of TGF-β/SMAD 2/3 and miR-192
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Abstract
<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" id="d1460712e134">Cyclophosphamide
(CP) is a widely used chemotherapeutic drug. However, the associated
nephrotoxicity restricts its clinical use.
</p>