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      LCZ696 (sacubitril/valsartan) protects against cyclophosphamide-induced nephrotoxicity in adult male rats: Up-regulation of Apelin-13/ACE2, miR-200, and down-regulation of TGF-β/SMAD 2/3 and miR-192

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      Life Sciences
      Elsevier BV

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          Abstract

          <p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" id="d1460712e134">Cyclophosphamide (CP) is a widely used chemotherapeutic drug. However, the associated nephrotoxicity restricts its clinical use. </p>

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          Author and article information

          Journal
          Life Sciences
          Life Sciences
          Elsevier BV
          00243205
          October 2022
          October 2022
          : 306
          : 120850
          Article
          10.1016/j.lfs.2022.120850
          35917938
          c4baf7bf-f902-4a18-91d4-2da3d98c37a5
          © 2022

          https://www.elsevier.com/tdm/userlicense/1.0/

          https://doi.org/10.15223/policy-017

          https://doi.org/10.15223/policy-037

          https://doi.org/10.15223/policy-012

          https://doi.org/10.15223/policy-029

          https://doi.org/10.15223/policy-004

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