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Effect of bowel transection and fecal passage deprivation on the enteric nervous system in neonatal rats.

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      Abstract

      A temporary stoma is a relatively common procedure at the neonatal age for a number of disorders. At birth, the enteric nervous system (ENS) is not fully developed; temporary colostomy causes morphological changes in the ENS. We studied whether transection of bowel or deprivation of stool is responsible for these changes. Moreover, reversibility of the ENS changes after stoma closure was investigated.

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      Affiliations
      [1 ] Department of Surgery, University Hospital Maastricht, 6202 AZ Maastricht, The Netherlands.
      Journal
      J. Pediatr. Surg.
      Journal of pediatric surgery
      Elsevier BV
      1531-5037
      0022-3468
      Oct 2008
      : 43
      : 10
      18926218 S0022-3468(08)00427-2 10.1016/j.jpedsurg.2008.04.031

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