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      Fast growing papillary renal cell carcinoma in first trimester pregnancy with postoperative inferior vena cava thrombosis: A case report

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          Abstract

          Renal cell carcinoma (RCC) is an extremely rare and fatal tumor for women of childbearing age. Consequently, the cases published in the literature are limited and medical experience with therapeutic management of newly diagnosed RCC in pregnant women is poor. We report our clinical experience with a renal tumor diagnosed in first-trimester pregnancy complicated in postoperative by an inferior vena cava thrombosis. Further reporting of such a case should help to collect more data in purpose to establish a clear, systematic and evidence guide-ligne in front of this unique situation.

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          Cancer and pregnancy: poena magna, not anymore.

          Cancer diagnosed during pregnancy constitutes a difficult clinical condition with a devastating impact on the patient's somatic and psychosocial health and possibly on foetal integrity. This circumstance also raises several moral, religious, social and familial dilemmas. In this review we critically present available evidence regarding the incidence, epidemiology and genetics of cancer in pregnant women, its presentation, diagnosis and staging as well as therapeutic management. Issues such as maternal/foetal prognosis, need for termination of pregnancy, risk of foetal health injury and necessity of psychosocial support are reviewed. Recent accumulating evidence suggests that, with appropriate management, poena magna should not be used to define neither cancer nor pregnancy.
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            Renal cell carcinoma in pregnancy: still a management challenge

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              [Renal masses in pregnancy. Diagnostics and therapeutic management].

              Cancer is the second most common cause of death in women of childbearing age. However, renal cell carcinoma (RCC) is a rare tumor in this collective with an incidence far below 5/100,000 cases per year. Therefore, medical experience with respect to diagnostics and therapeutic management of newly diagnosed RCC in pregnant women is scarce and the number of published cases low. However, recent studies indicated that higher estrogen levels and multigravidity could be associated with a higher risk of RCC. The aim of this article is to summarize the clinical experience in treating pregnant women with renal cancer against the background of those cases published in the literature.
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                Author and article information

                Contributors
                Journal
                Urol Case Rep
                Urol Case Rep
                Urology Case Reports
                Elsevier
                2214-4420
                01 June 2020
                November 2020
                01 June 2020
                : 33
                : 101292
                Affiliations
                [1]Department of Urology, Mohamed VI University Hospital Center, Mohamed I University, Oujda, Morocco
                Author notes
                []Corresponding author. boukhannous.1@ 123456gmail.com
                Article
                S2214-4420(20)30180-7 101292
                10.1016/j.eucr.2020.101292
                7276557
                d201c34e-a113-4eb3-8b9a-50e923f4925f
                © 2020 The Authors

                This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

                History
                : 24 May 2020
                : 28 May 2020
                : 31 May 2020
                Categories
                Oncology

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