81
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Anti-inflammatory cytokines.

      1 ,
      Chest
      Elsevier BV

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          The anti-inflammatory cytokines are a series of immunoregulatory molecules that control the proinflammatory cytokine response. Cytokines act in concert with specific cytokine inhibitors and soluble cytokine receptors to regulate the human immune response. Their physiologic role in inflammation and pathologic role in systemic inflammatory states are increasingly recognized. Major anti-inflammatory cytokines include interleukin (IL)-1 receptor antagonist, IL-4, IL-6, IL-10, IL-11, and IL-13. Specific cytokine receptors for IL-1, tumor necrosis factor-alpha, and IL-18 also function as proinflammatory cytokine inhibitors. The nature of anti-inflammatory cytokines and soluble cytokine receptors is the focus of this review. The current and future therapeutic uses of these anti-inflammatory cytokines are also reviewed.

          Related collections

          Author and article information

          Journal
          Chest
          Chest
          Elsevier BV
          0012-3692
          0012-3692
          Apr 2000
          : 117
          : 4
          Affiliations
          [1 ] Infectious Disease Division, Brown University School of Medicine, Providence, RI, USA. Steven_Opal@brown.edu
          Article
          S0012-3692(15)32820-8
          10.1378/chest.117.4.1162
          10767254
          4e68ed46-ecc0-4f78-993b-2866c83d45dd
          History

          Comments

          Comment on this article