Draft Genome Sequence of Methicillin-Sensitive Staphylococcus aureus ATCC 29213

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Abstract

Staphylococcus aureus subsp. aureus ATCC 29213 is one of the most commonly used strains in drug discovery research and for quality control. We report the completed draft genome sequence for the strain.

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Community-associated methicillin-resistant Staphylococcus aureus: epidemiology and clinical consequences of an emerging epidemic.

Michael David, Robert S Daum (2010)

Staphylococcus aureus is an important cause of skin and soft-tissue infections (SSTIs), endovascular infections, pneumonia, septic arthritis, endocarditis, osteomyelitis, foreign-body infections, and sepsis. Methicillin-resistant S. aureus (MRSA) isolates were once confined largely to hospitals, other health care environments, and patients frequenting these facilities. Since the mid-1990s, however, there has been an explosion in the number of MRSA infections reported in populations lacking risk factors for exposure to the health care system. This increase in the incidence of MRSA infection has been associated with the recognition of new MRSA clones known as community-associated MRSA (CA-MRSA). CA-MRSA strains differ from the older, health care-associated MRSA strains; they infect a different group of patients, they cause different clinical syndromes, they differ in antimicrobial susceptibility patterns, they spread rapidly among healthy people in the community, and they frequently cause infections in health care environments as well. This review details what is known about the epidemiology of CA-MRSA strains and the clinical spectrum of infectious syndromes associated with them that ranges from a commensal state to severe, overwhelming infection. It also addresses the therapy of these infections and strategies for their prevention.

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Draft Genome Sequences of Clinical Daptomycin-Nonsusceptible Methicillin-Resistant Staphylococcus aureus (MRSA) Strain APS211 and Its Daptomycin-Susceptible Progenitor APS210

David R. Cameron, Jhih-Hang Jiang, Iain J. Abbott … (2015)

To assess the genetic factors contributing to daptomycin resistance in Staphylococcus aureus, the draft genome of a clinically derived daptomycin-nonsusceptible isolate APS211 was generated and compared to the draft sequence of its susceptible progenitor strain APS210. Four genetic differences were identified including a previously described mutation within the mprF gene.

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Author and article information

Journal

Journal ID (nlm-ta): Genome Announc

Journal ID (iso-abbrev): Genome Announc

Journal ID (hwp): ga

Journal ID (pmc): ga

Journal ID (publisher-id): GA

Title: Genome Announcements

Publisher: American Society for Microbiology (1752 N St., N.W., Washington, DC )

ISSN (Electronic): 2169-8287

Publication date (Electronic): 24 September 2015

Publication date Collection: Sep-Oct 2015

Volume: 3

Issue: 5

Electronic Location Identifier: e01095-15

Affiliations

[a ]Division of Microbiology, CSIR-Central Drug Research Institute, UP, Lucknow, India

[b ]Department of Chemistry, IISER Pune, Maharashtra, India

Author notes

Address correspondence to Sidharth Chopra, skchopra007@ 123456gmail.com .

Article

Publisher ID: genomeA01095-15

DOI: 10.1128/genomeA.01095-15

PMC ID: 4582586

PubMed ID: 26404610

SO-VID: 7f4f1051-e0e1-43fc-b91d-fffe12248a15

License:

This is an open-access article distributed under the terms of the Creative Commons Attribution 3.0 Unported license.

History

Date received : 8 August 2015

Date accepted : 17 August 2015

Page count

Figures: 0, Tables: 0, Equations: 0, References: 4, Pages: 1, Words: 804

Custom metadata

cover-date September/October 2015

access-type free

ScienceOpen disciplines: Genetics

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ScienceOpen disciplines: Genetics

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