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      The Subaxial Cervical Pedicle Screw for Cervical Spine Diseases: The Review of Technical Developments and Complication Avoidance

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          Abstract

          This study aimed to review information on the subaxial cervical pedicle screw (CPS) including recent anatomical considerations, entry points, placement techniques, accuracy, learning curve, and complications. Relevant literatures were reviewed, and the authors’ experiences were summarized. The CPS is used for reconstruction of unstable cervical spine and achieves superior biomechanical stability compared to other fixation techniques. Various insertion and guidance techniques are established, among which, lateral fluoroscopy-assisted placement is the most common and cost-effective technique. Generally, placement under imaging guidance is more accurate than other techniques, and a three-dimensional template allows optimal trajectory for each pedicle regardless of intraoperative changes in spinal alignment. The free-hand technique using a curved pedicle probe without a funnel-like hole increases screw stability and reduces operation time, radiation exposure, and soft tissue injury. Compared to conventional lateral fluoroscopy-assisted placement, free-hand CPS placement by trained surgeons achieves superior accuracy comparable to that of image-guided navigation; in general, 30 training cases are sufficient for learning a safe and accurate technique for CPS placement. The complications of subaxial CPS are classified into three categories: complications due to screw misplacement, complications without screw misplacement, and others. Inexperienced surgeons may benefit from advanced techniques; however, the accuracy of CPS ultimately depends on the surgeon’s experience. Inexperienced surgeons should master the placement of the thoracolumbar pedicle screw in real practice and practice CPS insertion using cadavers. During the initial phase of the learning curve, careful preparation of surgery, reiterated identification, patterned safety steps, and supervision of the expert are necessary.

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          Most cited references54

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          Complications of pedicle screw fixation in reconstructive surgery of the cervical spine.

          Retrospective evaluation of complications in 180 consecutive patients with cervical disorders who had been treated by using pedicle screw fixation systems. To determine the risks associated with pedicle screw fixation in the cervical spine and to emphasize the importance of preoperative planning and surgical techniques in reducing the risks of this procedure. Generally, pedicle screw fixation in the cervical spine has been considered too risky for the neurovascular structures. There have been several reports describing the complications of lateral mass screw-plate fixation. However, no studies have examined in detail the complications associated with cervical pedicle screw fixation. One hundred eighty patients who underwent cervical reconstructive surgery using cervical pedicle screw fixation were reviewed to clarify the complications associated with the pedicle screw fixation procedure. Cervical disorders were spinal injuries in 70 patients and nontraumatic lesions in 110 patients. Seven hundred twelve screws were inserted into the cervical pedicles, and the locations of 669 screws were radiologically evaluated. Injury of the vertebral artery occurred in one patient. The bleeding was stopped by bone wax, and no neurologic complication developed after surgery. On computed tomographic (CT) scan, 45 screws (6.7%) were found to penetrate the pedicle, and 2 of 45 screws caused radiculopathy. Besides these three neurovascular complications directly attributed to screw insertion, radiculopathy caused by iatrogenic foraminal stenosis from excessive reduction of the translational deformity was observed in one patient. The incidence of the clinically significant complications caused by pedicle screw insertion was low. Complications associated with cervical pedicle screw fixation can be minimized by sufficient preoperative imaging studies of the pedicles and strict control of screw insertion. Pedicle screw fixation is a useful procedure for reconstruction of the cervical spine in various kinds of disorders and can be performed safely.
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            Transpedicular screw fixation for traumatic lesions of the middle and lower cervical spine: description of the techniques and preliminary report.

            Thirteen patients with fractures and/or dislocations of the middle and lower cervical spine were treated by transpedicular screw fixation using the Steffee variable screw placement system. Postoperative immobilization was either not used or simplified to short-term use of a soft neck collar. Recovery of nerve function and correction of kyphotic and/or translational deformities were satisfactory. All patients had solid fusion without loss of correction at the latest follow-up. There were no neurovascular complications. It was concluded that transpedicular screw fixation is as strong a fixation procedure for the cervical spine as it is for the thoracic and lumbar spine. This surgical procedure is associated with some risks of major neurovascular injuries; however, safety is adequate if the procedure is performed by experienced surgeons using meticulous surgical techniques.
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              Cervical human vertebrae. Quantitative three-dimensional anatomy of the middle and lower regions.

              In this study, the three-dimensional quantitative anatomy of middle and lower cervical vertebrae was determined. The three-dimensional coordinates of various marked points on the surface of the vertebra were measured with a specially designed morphometer instrument. From these coordinates, linear dimensions, angulations, and areas of surfaces and cross-sections of most vertebral components were calculated. The results showed two distinct transition regions: 1) toward the thoracic spine by the wider C7 vertebra but narrower spinal canal; and 2) toward the upper cervical region with the larger pedicle and spinous process of C2. Based on the study of 72 human cervical vertebrae, mean and standard error of the mean values of some clinically important dimensions of vertebral body, spinal canal, pedicles, transverse processes, spinous process, and uncovertebral joints are given for C2-C7 vertebrae. The areas of the end plates, spinal canal, and pedicles were modeled by elliptical and triangular shapes, and results were compared with the actual measurements.
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                Author and article information

                Journal
                Neurol Med Chir (Tokyo)
                Neurol. Med. Chir. (Tokyo)
                NMC
                Neurologia medico-chirurgica
                The Japan Neurosurgical Society
                0470-8105
                1349-8029
                May 2020
                15 April 2020
                : 60
                : 5
                : 231-243
                Affiliations
                [1 ]Department of Neurosurgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea;
                [2 ]Department of Emergency Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, Korea;
                [3 ]Department of Neurosurgery, Inje University Ilsan Paik Hospital, Neuroscience and Radiosurgery Hybrid Research Center, College of Medicine, Goyang, Korea
                Author notes
                Address reprint requests to: Jin Hoon Park, MD, PhD, Department of Neurosurgery, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Korea. e-mail: jhpark@ 123456amc.seoul.kr
                Article
                nmc-60-231
                10.2176/nmc.ra.2019-0189
                7246229
                32295984
                8b6dbf06-8e54-41c0-9835-407cd7989817
                © 2020 The Japan Neurosurgical Society The Japan Neurosurgical Society

                This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/

                History
                : 23 August 2019
                : 17 February 2020
                Categories
                Review Article

                cervical spine,pedicle screw,internal fixation,learning curve

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