[1
]Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, UK
[2
]National Institute for Health Research Blood and Transplant Research Unit (NIHR BTRU)
in Donor Health and Genomics, University of Cambridge, Cambridge, CB1 8RN, UK
[3
]Department of Epidemiology, University of Washington, Seattle, WA, 98109, USA
[4
]Division of Hematology/Oncology, Boston Children’s Hospital and Department of Pediatric
Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, 02115,
USA
[5
]Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA
[6
]Harvard-MIT Health Sciences and Technology, Harvard Medical School, Boston, MA, 02142,
USA
[7
]Department of Public Health and Primary Care, British Heart Foundation Cardiovascular
Epidemiology Unit, University of Cambridge, Cambridge, CB1 8RN, UK
[8
]MRC Biostatistics Unit, University of Cambridge, Cambridge, CB2 0SR, UK
[9
]Montreal Heart Institute, Montreal, Quebec, H1T 1C8, Canada
[10
]National Institute for Health Research Cambridge Biomedical Research Centre, University
of Cambridge and Cambridge University Hospitals, Cambridge, CB2 0QQ, UK
[11
]The Framingham Heart Study, National Heart, Lung and Blood Institute, Framingham,
MA, 01702, USA
[12
]Population Sciences Branch, Division of Intramural Research, National Heart, Lung
and Blood Institute, Framingham, MA, 01702, USA
[13
]Department of Genetics, University of North Carolina, Chapel Hill, NC, 27599, USA
[14
]Center for Population Genomics, Massachusetts Veterans Epidemiology Research and Information
Center (MAVERIC), VA Boston Healthcare System, Boston, MA, 02130, USA
[15
]Department of Public Health and Primary Care, Cambridge Baker Systems Genomics Initiative,
University of Cambridge, Cambridge, CB1 8RN, UK
[16
]Cambridge Baker Systems Genomics Initiative, Baker Heart and Diabetes Institute, Melbourne,
Victoria, VIC 3004, Australia
[17
]British Heart Foundation Centre of Excellence, Division of Cardiovascular Medicine,
Addenbrooke’s Hospital, Cambridge, CB2 0QQ, UK
[18
]Department of Haematology, University of Cambridge, Cambridge, CB2 0PT, UK
[19
]National Institute for Health Research (NIHR) BioResource, Cambridge University Hospitals,
Cambridge, CB2 0PT, UK
[20
]National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge,
CB2 0PT, UK
[21
]Department of Statistical Genetics, Osaka University Graduate School of Medicine,
Suita, Osaka, 565-0871, Japan
[22
]Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences,
Yokohama, Kanagawa, 230-0045, Japan
[23
]Icahn School of Medicine at Mount Sinai, The Charles Bronfman Institute for Personalized
Medicine, New York, NY, 10029, USA
[24
]Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, WI,
53201, USA
[25
]Department of Statistics and Operation Research, University of North Carolina, Chapel
Hill, NC, 27599, USA
[26
]Department of Ocular Pathology and Imaging Science, Graduate School of Medical Sciences,
Kyushu University, Fukuoka, 812-8581, Japan
[27
]Department of Biostatistics, University of Washington, Seattle, WA, 98101, USA
[28
]Population Health Sciences, Bristol Medical School, University of Bristol, Bristol,
BS8 1QU, UK
[29
]Translational Health Sciences, Musculoskeletal Research Unit, Bristol Medical School,
University of Bristol, Bristol, BS10 5NB, UK
[30
]Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and
Medical Sciences, University of Copenhagen, Copenhagen, 2200, Denmark
[31
]Hasso-Plattner-Institut, Universität Potsdam, Potsdam, 14469, Germany
[32
]Department of Medicine, University of Washington, Seattle, WA, 98101, USA
[33
]Department of Epidemiology, Erasmus University Medical Center Rotterdam, Rotterdam,
3015 GE, the Netherlands
[34
]Laboratory of Epidemiology and Population Science, National Institute on Aging/NIH,
Baltimore, MD, 21224, USA
[35
]Atlanta VA Medical Center, Decatur, GA, 30033, USA
[36
]Division of Research, Kaiser Permanente Northern California, Oakland, CA, 94612, USA
[37
]Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge,
Cambridge, CB10 1SA, UK
[38
]British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge,
CB1 8RN, UK
[39
]Section of Nutrition and Metabolism, International Agency for Research on Cancer,
Lyon, 69008, France
[40
]Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina,
45110, Greece
[41
]Department of Internal Medicine, Section of Gerontology and Geriatric Medicine, Wake
Forest School of Medicine, Winston-Salem, NC, 27101, USA
[42
]Department of Epidemiology and Biostatistics, Imperial College London, London, W2
1PG, UK
[43
]Imperial Biomedical Research Centre, Imperial College London and Imperial College
NHS Healthcare Trust, London, W2 1NY, UK
[44
]Medical Research Council Centre for Environment and Health, Imperial College London,
London, W2 1PG, UK
[45
]UK Dementia Research Institute, Imperial College London, London, WC1E 6BT, UK
[46
]Health Data Research UK London, London, W2 1PG, UK
[47
]Department of Internal Medicine B, University Medicine Greifswald, Greifswald, 17475,
Germany
[48
]German Center for Cardiovascular Research (DZHK), Partner Site Greifswald, Greifswald,
17475, Germany
[49
]Department of Epidemiology, University of Washington, Seattle, WA, 98101, USA
[50
]Department of Internal Medicine, Erasmus University Medical Center Rotterdam, Rotterdam,
3015 GE, the Netherlands
[51
]Department of Neurology, University of Pennsylvania, Philadelphia, PA, 19104, USA
[52
]Institute for Immunology and Transfusion Medicine, University Medicine Greifswald,
Greifswald, 17475, Germany
[53
]Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle,
WA, 98101, USA
[54
]Novo Nordisk Research Centre Oxford, Oxford, OX3 7FZ, UK
[55
]Department of Genetics, Shanghai-MOST Key Laboratory of Health and Disease Genomics,
Chinese National Human Genome Center and Shanghai Industrial Technology Institute
(SITI), Shanghai, 201203, China
[56
]Interfaculty Institute of Genetics and Functional Genomics, University Medicine Greifswald,
Greifswald, 17475, Germany
[57
]Chair of Experimental Bioinformatics, Research Group Computational Systems Medicine,
Technical University of Munich, Freising-Weihenstephan, 85354, Germany
[58
]Department of Clinical Physiology, Tampere University Hospital, Tampere, 33521, Finland
[59
]Department of Clinical Physiology, Finnish Cardiovascular Research Center - Tampere,
Faculty of Medicine and Health Technology, Tampere University, Tampere, 33014, Finland
[60
]Laboratory of Complex Trait Genomics, Department of Computational Biology and Medical
Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, 108-8639,
Japan
[61
]Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston,
MA, 02114, USA
[62
]Department of Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora,
CO, 80045, USA
[63
]Department of Clinical Chemistry, Fimlab Laboratories, Tampere, 33520, Finland
[64
]Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere,
Faculty of Medicine and Health Technology, Tampere University, Tampere, 33014, Finland
[65
]Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital,
Frederiksberg, 2000, Denmark
[66
]Department of Clinical Medicine, Faculty of Health and Medical Sciences, University
of Copenhagen, Copenhagen, 2200, Denmark
[67
]Department of Medicine, Division of Cardiology, Duke Molecular Physiology Institute,
Duke University Medical Center, Durham, NC, 27701, USA
[68
]Center for Public Health Genomics, University of Virginia, Charlottesville, VA, 22903,
USA
[69
]Department of Computational Biology and Medical Sciences, Graduate school of Frontier
Sciences, The University of Tokyo, Tokyo, 108-8639, Japan
[70
]Division of Molecular Pathology, The Institute of Medical Science, The University
of Tokyo, Tokyo, 108-8639, Japan
[71
]Department of Cardiology, Heart Center, Tampere University Hospital, Tampere, 33521,
Finland
[72
]Department of Cardiology, Finnish Cardiovascular Research Center - Tampere, Faculty
of Medicine and Health Technology, Tampere University, Tampere, 33014, Finland
[73
]Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis,
MN, 55455, USA
[74
]Departments of Epidemiology, University of Washington, Seattle, WA, 98101, USA
[75
]Department of Health Services, University of Washington, Seattle, WA, 98101, USA
[76
]Kaiser Permanente Washington Health Research Institute, Seattle, WA, 98101, USA
[77
]Centre for Population Health Research, University of Turku and Turku University Hospital,
Turku, 20521, Finland
[78
]Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku,
Turku, 20521, Finland
[79
]Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital,
Turku, 20521, Finland
[80
]Department of Biostatistics, University of North Carolina, Chapel Hill, NC, 27599,
USA
[81
]Department of Pediatrics, The Institute for Translational Genomics and Population
Sciences, The Lundquist Institute for Biomedical Innovation (formerly Los Angeles
Biomedical Research Institute) at Harbor-UCLA Medical Center, Torrance, CA, 90502,
USA
[82
]Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA
Boston Healthcare System, Boston, MA, 02130, USA
[83
]Department of Biostatistics and Epidemiology, University of Massachusetts-Amherst,
Amherst, MA, 01002, USA
[84
]Health Data Research UK Cambridge, Wellcome Sanger Institute, Hinxton, CB10 1SA, UK
[85
]Department of Public Health and Primary Care, Rutherford Fund Fellow, University of
Cambridge, Cambridge, CB1 8RN, UK
[86
]Department of Genetics, Stanford University School of Medicine, Stanford, CA, 94305,
USA
[87
]Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, Quebec,
H3T 1J4, Canada
[88
]Department of Genetics, School of Medicine, Mashhad University of Medical Sciences,
Mashhad, 9177948564, Iran
[89
]Institute for Community Medicine, University Medicine Greifswald, Greifswald, 17475,
Germany
[90
]The Alan Turing Institute, London, NW1 2DB, UK
[91
]Department of Medicine, Division on Aging, Brigham and Women’s Hospital, Boston, MA,
02115, USA
[92
]Department of Medicine, Harvard Medical School, Boston, MA, 02115, USA
[93
]Department of Computer Science, University of North Carolina, Chapel Hill, NC, 27599,
USA
[94
]Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK
[95
]Unit of Animal Genomics, GIGA-R & Faculty of Veterinary Medicine, University of Liège,
Liège, B-4000, Belgium
[96
]European Bioinformatics Institute, European Molecular Biology Laboratory, Hinxton,
CB10 1SA, UK
[97
]Laboratory of Statistical Immunology, Osaka University Graduate School of Medicine,
Suita, Osaka, 565-0871, Japan
[98
]BRC Haematology Theme and Radcliffe Department of Medicine, University of Oxford,
John Radcliffe Hospital, Oxford, OX3 9DU, UK
[99
]NHSBT Blood and Transplant - Oxford Center, John Radcliffe Hospital, Oxford, OX3 9BQ,
UK
