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MicroRNA-217-5p ameliorates endothelial cell apoptosis induced by ox-LDL by targeting CLIC4
October 2019
October 2019
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Abstract
Endothelial cell apoptosis plays an essential role in the pathogenesis of atherosclerosis.
MicroRNAs and chloride intracellular channels (CLICs) have been verified to participate
in the endothelial cell apoptosis process, however, the underlying molecular mechanisms
are still unclear. The main aim of this study was to investigate the biological effects
of microRNA-217-5p (miR-217-5p) and CLIC4 on endothelial cell apoptosis in atherosclerosis.