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      Detection of renal cell hydronephrosis in ultrasound kidney images: a study on the efficacy of deep convolutional neural networks

      1 , 2 , 3 , 4 , 5 , 6
      PeerJ Computer Science
      PeerJ

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          Abstract

          In the realm of medical imaging, the early detection of kidney issues, particularly renal cell hydronephrosis, holds immense importance. Traditionally, the identification of such conditions within ultrasound images has relied on manual analysis, a labor-intensive and error-prone process. However, in recent years, the emergence of deep learning-based algorithms has paved the way for automation in this domain. This study aims to harness the power of deep learning models to autonomously detect renal cell hydronephrosis in ultrasound images taken in close proximity to the kidneys. State-of-the-art architectures, including VGG16, ResNet50, InceptionV3, and the innovative Novel DCNN, were put to the test and subjected to rigorous comparisons. The performance of each model was meticulously evaluated, employing metrics such as F1 score, accuracy, precision, and recall. The results paint a compelling picture. The Novel DCNN model outshines its peers, boasting an impressive accuracy rate of 99.8%. In the same arena, InceptionV3 achieved a notable 90% accuracy, ResNet50 secured 89%, and VGG16 reached 85%. These outcomes underscore the Novel DCNN’s prowess in the realm of renal cell hydronephrosis detection within ultrasound images. Moreover, this study offers a detailed view of each model’s performance through confusion matrices, shedding light on their abilities to categorize true positives, true negatives, false positives, and false negatives. In this regard, the Novel DCNN model exhibits remarkable proficiency, minimizing both false positives and false negatives. In conclusion, this research underscores the Novel DCNN model’s supremacy in automating the detection of renal cell hydronephrosis in ultrasound images. With its exceptional accuracy and minimal error rates, this model stands as a promising tool for healthcare professionals, facilitating early-stage diagnosis and treatment. Furthermore, the model’s convergence rate and accuracy hold potential for enhancement through further exploration, including testing on larger and more diverse datasets and investigating diverse optimization strategies.

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          Most cited references25

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          Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy

          Type 2 diabetes mellitus is the leading cause of kidney failure worldwide, but few effective long-term treatments are available. In cardiovascular trials of inhibitors of sodium-glucose cotransporter 2 (SGLT2), exploratory results have suggested that such drugs may improve renal outcomes in patients with type 2 diabetes.
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            Kidney Stone Disease: An Update on Current Concepts

            Kidney stone disease is a crystal concretion formed usually within the kidneys. It is an increasing urological disorder of human health, affecting about 12% of the world population. It has been associated with an increased risk of end-stage renal failure. The etiology of kidney stone is multifactorial. The most common type of kidney stone is calcium oxalate formed at Randall's plaque on the renal papillary surfaces. The mechanism of stone formation is a complex process which results from several physicochemical events including supersaturation, nucleation, growth, aggregation, and retention of urinary stone constituents within tubular cells. These steps are modulated by an imbalance between factors that promote or inhibit urinary crystallization. It is also noted that cellular injury promotes retention of particles on renal papillary surfaces. The exposure of renal epithelial cells to oxalate causes a signaling cascade which leads to apoptosis by p38 mitogen-activated protein kinase pathways. Currently, there is no satisfactory drug to cure and/or prevent kidney stone recurrences. Thus, further understanding of the pathophysiology of kidney stone formation is a research area to manage urolithiasis using new drugs. Therefore, this review has intended to provide a compiled up-to-date information on kidney stone etiology, pathogenesis, and prevention approaches.
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              Clear cell renal cell carcinoma: CT-based radiomics features for the prediction of Fuhrman grade

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                Author and article information

                Journal
                PeerJ Computer Science
                PeerJ
                2376-5992
                2024
                January 23 2024
                : 10
                : e1797
                Affiliations
                [1 ]Department of Computer Science, IQRA National Swat Campus, KPK, Pakistan
                [2 ]Department of Computer Science, Applied College, University of Tabuk, Tabuk, Saudi Arabia
                [3 ]College of Computer and Information Sciences, Jouf University, Jouf, Saudi Arabia
                [4 ]Department of Computer Science, IQRA National Swat Campus, Swat, KPK, Pakistan
                [5 ]Department of Computer Engineering, Gachon University, Seongnam-si, Republic of South Korea
                [6 ]Department of Computer Science and Information Systems, College of Applied Sciences, AlMaarefa University, Riyadh, Saudi Arabia
                Article
                10.7717/peerj-cs.1797
                a1523710-7b7b-4b8d-8684-e00d0381a943
                © 2024

                https://creativecommons.org/licenses/by/4.0/

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