GoMiner: a resource for biological interpretation of genomic and proteomic data

Abstract

GoMiner, a program package that organizes lists of 'interesting' genes for biological interpretation in the context of the Gene Ontology, has been developed.

Abstract

We have developed GoMiner, a program package that organizes lists of 'interesting' genes (for example, under- and overexpressed genes from a microarray experiment) for biological interpretation in the context of the Gene Ontology. GoMiner provides quantitative and statistical output files and two useful visualizations. The first is a tree-like structure analogous to that in the AmiGO browser and the second is a compact, dynamically interactive 'directed acyclic graph'. Genes displayed in GoMiner are linked to major public bioinformatics resources.

Journal

Journal ID (nlm-ta): Genome Biol

Title: Genome Biology

Publisher: BioMed Central (London )

ISSN (Print): 1465-6906

ISSN (Electronic): 1465-6914

Publication date (Print): 2003

Publication date (Electronic): 25 March 2003

Volume: 4

Issue: 4

Page: R28

Affiliations

[1 ]Genomics and Bioinformatics Group, Laboratory of Molecular Pharmacology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA

[2 ]The Wallace H. Coulter Biomedical Engineering Department, Georgia Institute of Technology and Emory University, Atlanta, GA 30332-0535, USA

[3 ]Computer Science and Chemistry Departments, Georgia Institute of Technology, Atlanta, GA 30332, USA

[4 ]SRA International, 4300 Fair Lakes CT, Fairfax, VA 22033, USA

[5 ]Laboratory of Biosystems and Cancer, National Cancer Institute, Bethesda, MD 20892, USA

Correspondence: John N Weinstein. E-mail: [e-mail]

Article

Publisher ID: gb-2003-4-4-r28

DOI: 10.1186/gb-2003-4-4-r28

PMC ID: 154579

PubMed ID: 12702209

Copyright statement: Copyright © 2003 Zeeberg et al.; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL.

Categories

Subject: Software